match idtarget lengthalignment lengthprobabilityE-valuecoveragematch description
1cd0917813413399.24.8E-11[---------                                        ]PLDc_N_Snf2_likeN-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family. N-terminal putative catalytic domain of uncharacterized archaeal and prokaryotic HKD family nucleases fused to putative helicases from the Snf2-like family, which belong to the DNA/RNA helicase superfamily II (SF2). Although Snf2-like family enzymes do not possess helicase activity, they contain a helicase-like region, where seven helicase-related sequence motifs are found, similar to those in DEAD/DEAH box helicases, which represent the biggest family within the SF2 superfamily. In addition to the helicase-like region, members of this family also contain an N-terminal putative catalytic domain with one copy of the conserved HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue), and have been classified as members of the phospholipase D (PLD, EC superfamily.
2cd000791319398.35.4E-06[                                  -----          ]HELICcHelicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may not be an autonomously folding unit, but an integral part of the helicase; 4 helicase superfamilies at present according to the organization of their signature motifs; all helicases share the ability to unwind nucleic acid duplexes with a distinct directional polarity; they utilize the free energy from nucleoside triphosphate hydrolysis to fuel their translocation along DNA, unwinding the duplex in the process
3pfam00271784697.98.1E-06[                                     --          ]Helicase_CHelicase conserved C-terminal domain. The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
4COG055386613097.10.17[                                  -------        ]HepASuperfamily II DNA or RNA helicase, SNF2 family
5pfam0017628614896.30.0015[            -------                              ]SNF2_NSNF2 family N-terminal domain. This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g., ERCC6, RAD16, RAD5), DNA recombination (e.g., RAD54), and chromatin unwinding (e.g., ISWI) as well as a variety of other proteins with little functional information (e.g., lodestar, ETL1).
6COG051351311993.30.26[                                  ------         ]SrmBSuperfamily II DNA and RNA helicase
7COG111154212392.60.47[                                 ------          ]MPH1ERCC4-related helicase
8pfam130911295092.40.17[      ---                                        ]PLDc_2PLD-like domain.
9PRK049149569890.30.13[                                  -----          ]PRK04914ATP-dependent helicase HepA; Validated
10PRK045375727277.42.1[                                    ----         ]PRK04537ATP-dependent RNA helicase RhlB; Provisional
11PRK111924348666.33.5[                                   -----         ]PRK11192ATP-dependent RNA helicase SrmB; Provisional
12PRK1376677312666.117[                                 ------          ]PRK13766Hef nuclease; Provisional
13PRK048374237664.77.9[                                    ----         ]PRK04837ATP-dependent RNA helicase RhlB; Provisional
14PRK117764607257.23.7[                                    ----         ]PRK11776ATP-dependent RNA helicase DbpA; Provisional
15PRK0491495611152.24.1[            ------                               ]PRK04914ATP-dependent helicase HepA; Validated
16cd000461444649.85.3[            --                                   ]DEXDcDEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
17PRK116346298249.013[                                     ----        ]PRK11634ATP-dependent RNA helicase DeaD; Provisional
18COG106144211737.422[                                  ------         ]SSL2Superfamily II DNA or RNA helicase
19pfam048511034830.17.8[            ---                                  ]ResIIIType III restriction enzyme, res subunit.
20pfam011251438628.378[                 -----                           ]G10G10 protein.
21COG120067711227.461[                                    -----        ]RecGRecG-like helicase
22PRK012974755827.341[                                     ---         ]PRK01297ATP-dependent RNA helicase RhlB; Provisional
23PRK1059045610825.552[                                 ------          ]PRK10590ATP-dependent RNA helicase RhlE; Provisional
24pfam1368022710823.955[                    -----                        ]DUF4152Protein of unknown function (DUF4152). This family of proteins is functionally uncharacterized. This family of proteins is found in archaea. Proteins in this family are approximately 230 amino acids in length. The structure of PF2046 from pyrococcus furiosus has been solved. It shows an RNaseH like fold that conserves critical catalytic residues. This suggests that these proteins may cleave nucleic acid.
25TIGR040954515323.436[                                     --          ]dnd_restrict_1DNA phosphorothioation system restriction enzyme. The DNA phosphorothioate modification system dnd (DNA instability during electrophoresis) recently has been shown to provide a modification essential to a restriction system. This protein family was detected by Partial Phylogenetic Profiling as linked to dnd, and its members usually are clustered with the dndABCDE genes.
26TIGR0064363011122.345[                                     -----       ]recGATP-dependent DNA helicase RecG.